Parinaud syndrome definition | Medical Term

Upgaze palsy. Parinaud syndrome medical term. Parinaud syndrome definition.

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Parinaud Syndrome Definition

Syndromes are ‘a group of signs and symptoms that occur together’ (Merriam-Webster dictionary, Oxford dictionary).

Parinaud syndrome a.k.a dorsal midbrain syndrome typically refers to 4 medical signs.

These are:

  • 1. Eyelid retraction a.k.a Collier’s sign
  • 2. Upgaze palsy a.k.a ‘sunset’ eyes a.k.a ‘Setting sun’ sign
  • 3. Convergence-retraction nystagmus
  • 4. Light-near dissociation (tectal pupils)

Causes of Parinaud syndrome

  • Compressing mass in the pineal region i.e. tumours or aneurysms
  • Dilation of the third ventricle or hydrocephalus
  • Cerebral infarction (stroke)
  • A-V malformations
  • Multiple Sclerosis

Treatment of Parinaud syndrome

Treatment is generally geared towards treating the cause, and symptom management.

Here is a British Medical Journal article on Henri Parinaud, the 19th Century French ophthalmologist, after whom this syndrome is named, and his observation of Parinaud’s syndrome.

Here is a PubMed article on Parinaud’s syndrome definition and its pathophysiology.

Note: MDScene is not affiliated with these inter/national journals, however, they are held in high regard within the scientific community and used by health professionals worldwide.


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